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MK outlet的問題,我們搜遍了碩博士論文和台灣出版的書籍,推薦Annaratone, Donatello寫的 Handbook for Heat Exchangers and Tube Banks Design 可以從中找到所需的評價。

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國立臺灣師範大學 生命科學系 鄭劍廷所指導 吳威毅的 膀胱泌尿上皮鈣離子感知接受器於排尿功能之調節角色以及其對於膀胱功能障礙之治療潛力 (2021),提出MK outlet關鍵因素是什麼,來自於鈣離子感知接受器、化學感知、逼尿肌、排尿、泌尿上皮。

而第二篇論文國立陽明交通大學 傳統醫藥研究所 許中華、陳方佩所指導 陳玉紅豔的 中藥(VGH-BPH1)對於良性攝護腺增生病人之療效評估 (2021),提出因為有 良性前列腺增生、中藥、隨機、雙盲、安慰劑對照交叉試驗的重點而找出了 MK outlet的解答。

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Handbook for Heat Exchangers and Tube Banks Design

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為了解決MK outlet的問題,作者Annaratone, Donatello 這樣論述:

The recently published book by the author, "Engineering Heat Transfer," already dealt with exact computation of heat exchangers and tube banks. In design c- putationthisisaccomplishedviacorrectivefactors;thelattermakesitpossibleto compute the actual mean temperature difference by starting from the l

ogarithmic onerelativeto?uidsinparallel?oworcounter?ow. As far as veri?cation computation is concerned, corrective factors were int- ducedtocomputeacertaincharacteristicfactorcorrectly, asisfundamentalforthis typeofcomputation. Basedontheabove, theauthordecidedtoinvestigatefurther, re?ne, andwiden t

histopic: theoutcomeofthisworkhasresultedinthishandbook. Newtypesofexchangerswereexamined;thecalculationwasre?nedtoproduce practicallyexactvaluesforthefactors. Thescopeoftheinvestigationwasincreased by widening the range of the starting factors. Furthermore, a greater number of valuestobeincludedint

hetableswasconsidered. Finally, afewcharacteristicsof certainvaluesofthecorrectivefactorswerehighlighted. The?rstsectionisanintroduction;itsummarizesthefundamentalcriteriaofheat transferandproceedstoillustratethebehaviorof?uidsinbothparallelandcounter ?ow. Italsoshowshowtocomputethemeanisobaricspeci

?cheatforsome?uids; itillustratesthesigni?canceofdesigncomputationandveri?cationcomputation. In addition, itillustrateshowtoproceedwithheatexchangersandtubebankstocarry outbothdesignandveri?cationcomputationcorrectly. AppendixAthenincludes36tablesasareferencefordesigncomputation, The tablescontainth

ecorrectivefactorsrequiredtoobtaintheactualmeantemperature differencebystartingfromthemeanlogarithmictemperaturedifferencerelativeto uidsinparallel?oworcounter?ow. Finally, Appendix B includes 35 tables for veri?cation computation. As far as heatexchangers areconcerned, itshowsthevaluesoffactor ? wh

ichisrequired forthistypeofcomputation. Thevaluesofthecorrectivefactorsforcoilsandtube banksarealsopresented. Milano, Italy DonatelloAnnaratone v Notation c=speci?cheat(J/kgK) d=diameter(m) E=ef?ciencyfactor h=enthalpy(kJ/kg) k=thermalconductivity(W/mK) M=mass?owrate(kg/s) m=massmoisturepercentage(%

) q=heatpertimeunit(W) 2 S=surface(m ) ? t=temperature( C) 2 U=overallheattransfercoef?cient(W/m K) x=thickness(m) 2 ? =heattransfercoef?cient(W/m K) ? =characteristicfactor ? =characteristicfactor ? =ef?ciency ? =correctivefactor ? =correctivefactor ? =characteristicfactor ? ?t=temperaturedifferenc

e( C) vii viii Notation Superscripts =heating?uid =heated?uid Subscripts c=counter?ow e=exchanger i=inside l=logarithmic m=mean o=outside p=constantpressure(isobaric), parallel?ow w=wall 1=inlet(forheatingorheated?uid) 2=outlet(forheatingorheated?uid) Contents 1 Introduction to Computation . . . . .

. . . . . . . . . . . . . . . . 1 1. 1 GeneralConsiderations . . . . . . . . . . . . . . . . . . . . . . 1 1. 2 MeanIsobaricSpeci?cHeat . . . . . . . . . . . . . . . . . . . . 3 1. 2. 1 WaterandSuperheatedSteam . . . . . . . . . . . . . . . 4 1. 2. 2 AirandOtherGases. . . . . . . . . . . . . . . .

. . . . 4 2 Design Computation. . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. 1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 2. 2 FluidsinParallelFloworinCounterFlow . . . . . . . . . . . . 8 2. 3 TheMeanDifferenceinTemperatureinReality . . . . . . . . . 12 2. 3. 1

FluidsinCrossFlow. . . . . . . . . . . . . . . . . . . . 14 2. 3. 2 HeatExchangers. . . . . . . . . . . . . . . . . . . . . . 15 2. 3. 3 Coils. . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 2. 3. 4 TubeBankswithVariousPassagesoftheExternalFluid . 21

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膀胱泌尿上皮鈣離子感知接受器於排尿功能之調節角色以及其對於膀胱功能障礙之治療潛力

為了解決MK outlet的問題,作者吳威毅 這樣論述:

鈣離子感知接受器能調節許多除了調鈣作用以外的生理功能。然而鈣離子感知接受器於下泌尿道功能中所扮演之角色仍尚未明瞭。本研究之目的為檢測大鼠的膀胱泌尿上皮細胞的鈣離子感知接受器是否能影響膀胱平滑肌的活性、排尿反射、骨盆神經活性、膀胱血液微循環以及膀胱炎引起的膀胱過度活躍。在此研究中,我們使用西方墨點法以與免疫組織化學染色來確認大鼠膀胱鈣離子感知接受器的表現以及表現位置。並使用離體肌肉張力儀來測定藉由專一促進劑(AC-265347)所活化的鈣離子感知接受器以及專一拮抗劑(NPS-2143)所抑制的鈣離子感知接受器如何分別去影響膀胱逼尿肌的自發性活性與收縮力。再使用膀胱壓力檢測、骨盆神經活性記錄、膀

胱表面血液微循環檢測來評估膀胱內灌注鈣離子感知接受器促進劑、鈣離子感知接受器拮抗劑、氯化鈣、以及含有鈣離子感知接受器拮抗劑之氯化鈣分別所產生的作用。除此之外我們還應用多種膀胱過度活躍或功能障礙之動物模式來評估鈣離子感知接受器促進劑對於膀胱過度活躍或功能障礙的治療潛力。在研究結果中我們藉由鈣離子感知接受器與泌尿上皮特異蛋白之共定位確認鈣離子感知接受器表現在膀胱泌尿上皮。在離體實驗中,泌尿上皮鈣離子感知接受器之活化會減低乙醯膽鹼所引發的膀胱平滑肌收縮,然而泌尿上皮鈣離子感知接受器之抑制會增加膀胱平滑肌的自發性收縮振幅與自發性收縮頻率。膀胱內灌注鈣離子感知接受器促進劑會抑制排尿頻率、非排尿收縮時期的

骨盆感覺神經活性、以及排尿時期的骨盆運動神經活性。膀胱內同時灌注鈣離子感知接受器拮抗劑與氯化鈣會增加排尿頻率以及骨盆感覺神經活性,然而單獨灌注氯化鈣或鈣離子感知接受器拮抗劑則無影響。除此之外,上述這些膀胱內灌注實驗處理皆不影響膀胱血液微循環。泌尿上皮鈣離子感知接受器之活化能改善膀胱過度活躍相關的尿路動力參數。我們確認泌尿上皮鈣離子感知接受器展現出化學感知功能,且是透過平滑肌與神經相關機制來調節排尿功能、而非透過膀胱血液動力之干擾來調節排尿功能,並能改善膀胱過度活躍。此研究提供了尿液中物質能透過泌尿上皮鈣離子感知接受器來調節排尿功能之有力證據,並指出泌尿上皮鈣離子感知接受器能於膀胱疾病的醫療介入

中作為一個具有潛在臨床應用價值的治療標的。

中藥(VGH-BPH1)對於良性攝護腺增生病人之療效評估

為了解決MK outlet的問題,作者陳玉紅豔 這樣論述:

良性前列腺增生(BPH)是 腺體組織出現非癌化的良性增生的疾病。這種疾病可以影響生活品質並引起併發症,例如膀胱壁厚、膀胱結石等。而西藥也可能會產生性慾降低以及勃起功能障礙等副作用。因此,有不少患者會主動尋求其他治療方法。一些過去研究表明,中藥可以減輕BPH患者的症狀。因此,本研究團隊進行隨機雙盲對照及交叉實驗,以研究中藥(VGH-BPH1)是否可以改善BPH症狀。VGH-BPH1的組成成分包括濟生腎氣丸、桑螵蛸散、覆盆子、益智仁、烏藥、丹參、淫羊藿、黃柏和知母。在這項研究中,收集了23名患者,隨機雙盲分派為A組與B組:在第1階段,為期8週,A組接受VGH-BPH1,而B組接受安慰劑。於八週結

束後,停藥兩週,並將兩組互換,在第2階段,A組改為服用安慰劑,B組改為服用VGH-BPH1,為期8週。同時,所有患者仍繼續接受西藥治療。受試者須於試驗前、第八週末、第十週始、第十八週末填寫國際攝護腺症狀評分 (International Prostate Symptom Score, IPSS)、老年男性症狀評分表(Aging Male Symptoms Score, AMS)、國際勃起功能指標量表(International index of erectile function, IIEF)以及中醫體質量表(Constitution in Chinese Medicine Questionn

aire,CCMQ),並且於使用中藥前、第八週末、第十週始、第十八週末分別測量尿流速(Uroflowmetry)以及尿後殘尿量(Post-void residual urine volume)。顯示,VGH-BPH1 顯著降低 IPSS 總分(p=0.027); 然而,與安慰劑組相比,沒有發現顯著差異。關於AMS,VGH-BPH1組的“關節痛及肌肉痛”評分顯著低於安慰劑組(p=0.022)。比較兩組時,“感覺過勞”評分也顯示出下降趨勢(p=0.057)。治療後,VGH-BPH1組與安慰劑組的IIEF,CCMQ,尿流速以及尿後殘尿量無統計學差異。雖然研究結果顯示VGH-BPH1的療效並未達到統計

顯著意義,但與安慰劑相比,在改善某些生活品質評估上具顯著意義。希望將來進行更大樣本數的臨床研究,來證實VGH-BPH1的療效。